Preventing INFECTION

 
 

What is an infection?

Your body’s normal reaction to having an illness or an infection is a fever. A fever is a body temperature that is higher than normal. For most people, normal is 98.6°F. Identifying and managing a fever early is important because infections can be serious in people with sickle cell disease.

Risks of an infection

  • Infections are one the most common causes of death in people with sickle cell disease.

  • The risk of infection is increased because the spleen — which acts as a filter for bacteria — does not work normally in people with sickle cell disease. In some cases, the spleen has been removed, In most cases, the spleen stops working to protect the body from infection in infancy.

  • Infections can happen in the blood, lungs, spinal fluid, or urinary tract system (kidneys and bladder).

 

What are the symptoms of an infection?

A fever is the most important, and sometimes only sign of infection:

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If your spleen has been removed, a fever is 100.5°F or higher.

If you still have your spleen, a fever is 101.5°F or higher.

Call your provider if you have a fever. You should be seen and checked for infection in the clinic or emergency room.


In order to help prevent an infection, you should:

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wash your hands often

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Make sure you have the right vaccinations

(see the Vaccines Prevent Life-Threatening Infections section for more information)

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Make sure you and other family members in the home get the flu shot every year.


 

Treatment

  • If you are not admitted to the hospital, you may be seen again the next day in clinic, or you may be called at home to see how you are doing.

  • If you are at home, but continue to have a fever 24 hours after being seen, you will need to go to the clinic or emergency room again for additional care.

  • Your provider may ask that you take penicillin every day, especially if you had an infection caused by bacteria or had your spleen removed.

 
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Fever checklist

For you and your health care provider

 

Penicillin

🄯 Your health care provider may ask that you take penicillin every day, especially if you had an infection caused by bacteria or had your spleen removed.


 
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Section overview

 
  • Infection is one of the most common causes of death in people with sickle cell disease.

  • Call your provider if you have a fever.