Acute chest syndrome (ACS) is a lung-related complication of sickle cell disease that can result in death.
Common symptoms of ACS include:
◦ Fever
◦ Cough
◦ Trouble breathing (fast, hard breathing)
◦ Chest pain
ACS can be caused by:
An infection in the lungs (pneumonia).
Blood clots or sickled cells blocking blood ow to the lungs.
Too much fluid in the lungs
Pain – it can be hard to take deep breaths.
People who have asthma are at greater risk, as are people who have just had surgery.
Treatment
You will be admitted to the hospital so you can be watched closely for difficulty breathing, low blood counts, low levels of oxygen in your blood, worsening chest X-ray results, and other complications. You may get:
oxygen
an incentive spirometer (expands your lungs so you can breathe better)
pain medicine
antibiotics
a blood transfusion
an exchange transfusion
Can ACS be prevented?
Expanding your lungs using an incentive spirometer, especially when you have pain, can help prevent ACS.
Medicines:
🄯 Talk with your provider about the medicines you are getting. The usual medicines given for ACS are antibiotics by mouth or through a vein to fight the infections. Your provider can give you more information about these medicines.
Common antibiotics include:
• cephalosporin
• macrolide
Oxygen levels:
🄯 If you have lower oxygen saturation levels, trouble breathing, or worsening lung x-ray results, talk with your provider about blood transfusions.
If your hemoglobin is low, you may need only a simple transfusion.
If your hemoglobin is higher, you may need a red cell exchange transfusion.
🄯 You may need to wear oxygen to keep your oxygen saturation in a higher range. You will also be encouraged to use an incentive spirometer frequently to help expand your lungs.
Incentive spirometer:
🄯 If you are admitted to the hospital for any reason, talk with your provider and get an incentive spirometer.
Symptoms include fever, cough, trouble breathing, and chest pain.
If you are admitted to the hospital for any reason, use an incentive spirometer to help your lungs work better.
Medicines for ACS are antibiotics taken by mouth or through a vein.
If you have low oxygen levels, trouble breathing, or worsening lung x-ray results, talk with your provider about a blood transfusion.